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A Randomized Phase 2 Study of the Efficacy and Tolerability of Veliparib in Combination with Temozolomide or Veliparib in Combination with Carboplatin and Paclitaxel Versus Placebo Plus Carboplatin and Paclitaxel in Subjects with BRCA1 or BRCA2 Mutation and Metastatic Breast Cancer
A Randomized Phase III Trial of Adjuvant Therapy
Comparing Chemotherapy Alone (Six Cycles of Docetaxel Plus Cyclophosphamide
or Four Cycles of Doxorubicin Plus Cyclophosphamide Followed by Weekly
Paclitaxel) to Chemotherapy Plus Trastuzumab in Women with Node-Positive
or High-Risk Node-Negative HER2-Low Invasive Breast Cancer
A Phase II Prospective Trial Correlating Progression
Free Survival with CYP2D6 Activity in Patients with Metastatic Breast
Cancer Treated with Single Agent Tamoxifen
A Randomized Phase III Trial of the Value of
Early Local Therapy for the Intact Primary Tumor in Patients with Metastatic
Breast Cancer
Randomized Phase II 2x2 Factorial Trial Of
The Addition of Carboplatin And/Or Bevacizumab To Neoadjuvant Weekly Paclitaxel
Followed By Dose-Dense AC In Hormone Receptor-Poor/HER2-Negative Resectable
Breast Cancer
A Randomized Multicenter, Double-Blind, Placebo-Controlled
Comparison of Chemotherapy plus Trastuzumab plus Placebo versus Chemotherapy
plus Trastuzumab plus Pertuzumab as adjuvant Therapy in Patients with
Operable HER2-positive Primary Breast Cancer
LUX: An open label, randomised phase III trial of BIBW
2992 and vinorelbine versus trastuzumab and vinorelbine in patients with
metastatic HER2-overexpressing breast cancer failing one prior trastuzumab
treatment
Lumpectomy and Brachytherapy as Salvage Treatment
for Local Recurrences Following Breast Conservative Therapy
Investigating Radiation Therapy: The
Accelerated RT Trial
Mammary Ductoscopy
and Intraductal Biopsy for Women at High Risk for Developing Breast Cancer,
for Women Presenting with Spontaneous Nipple Discharge, and for Women
Diagnosed with Breast Cancer Undergoing Surgery to the Contralateral Breast
A Phase III Trial Evaluating the Addition of Trastuzumab
to Trimodality Treatment of HER2-Overexpressing Esophageal Adenocarcinoma.
A Phase II Study For Patients With Advanced Rectal
Cancer Using Pre-Operative High Dose Rate Brachytherapy + Folfox Chemotherapy
A Phase III Trial of 6 Versus 12 Treatments
of Adjuvant FOLFOX Plus Celecoxib or Placebo for Patients with Resected
Stage III Colon Cancer.
A Phase III Randomized, Double-Blind Trial of Chemoembolization
with or without Sorafenib in Unresectable Hepatocellular Carcinoma (HCC)
in Patients with and without Vascular Invasion.
RTOG 0436: A Phase III Trials Evaluating the Addition
of Cetuximab to Paclitaxel, Cisplatin, and Radiation for Patients with
Esophageal Cancer Who Are Treated Without Surgery
GOG-0258: A Randomized Phase III Trial of Cisplatin
and Tumor Volume Directed Irradiation Followed by Carboplatin and Paclitaxel
vs. Carboplatin and Paclitaxel for Optimally Debulked, Advanced Endometrial
Carcinoma
Phase II Trial of Combination Pemetrexed
(Alimta) and Carboplatin (Paraplatin) in Platinum Sensitive Recurrent
Ovarian, Primary Peritoneal, and Fallopian Tube Carcinoma
GOG-0263: RANDOMIZED PHASE III CLINICAL TRIAL
OF ADJUVANT RADIATION VERSUS CHEMORADIATION IN INTERMEDIATE RISK, STAGE
I/IIA CERVICAL CANCER TREATED WITH INITIAL RADICAL HYSTERECTOMY AND PELVIC
LYMPHADENECTOMY.
Phase 1/2 Study of PX-866 and Docetaxel in Patients
with Solid Tumors
Prospective Evaluation of Unilateral/Ipsilateral
Neck Irradiation Combined with Amifostine in Selected Patients with Squamous
Cell Carcinoma of the Head and Neck Who are Managed by Radiation Therapy.
RTOG 0920: A Phase III Study of Postoperative
Radiation Therapy (IMRT) +/- Cetuximab for Locally-Advanced Resected Head
and Neck Cancer
A phase I trial of adjuvant chemotherapy using
cetuximab (c) and docetaxel (t) for N2b-3 HNSCC patients with positive
pathologic residual neck diseases after concurrent chemoradiation (CRT)
A Phase III Randomized Trial of Chemotherapy
With or Without Bevacizumab in Patients with Recurrent or Metastatic Head
and Neck Cancer
A Randomized Double-blinded Phase III Study
Comparing Gemcitabine, Cisplatin, and Bevacizumab to Gemcitabine, Cisplatin,
and Placebo in Patients with Advanced Transitional Cell Carcinoma
Abiraterone Acetate Treatment for Prostate
Cancer Patients with PSA of More Than Four Following Initial Androgen
Deprivation Therapy, Phase II
A Phase III Randomized Study of Oral Sapacitabine
In Elderly Patients with Newly Diagnosed Acute Myeloid Leukemia
Phase II Trial of Pentostatin, Cyclophosphamide
and Rituximab (PCR) Followed By Campath-1H For Previously Treated Relapsed
or Refractory Patients With Chronic Lymphocytic Leukemia
TTP: Phase II study of danazol with plasma exchange
and steroids for the treatment of thrombotic thrombocytopenic purpura
A Phase III Randomized Trial of Adjuvant Chemotherapy With or Without Bevacizumab for Patients With Completely Resected Stage IB (> 4 cm) -IIIA Non-Small Cell Lung Cancer (NSCLC)
ACOSOG Z4099/ RTOG 1021: A
Randomized Phase III Study of Sublobar Resection (+/- Brachytherapy) versus
Stereotactic Body Radiation Therapy in High Risk Patients with Stage I
Non-Small Cell Lung Cancer (NSCLC).
Surgical Cytoreduction Followed
by Intraoperative Intrathoracic Hyperthermic Chemotherapy Perfusion for
the Management of Disseminated Pleural Malignancies
Phase 1/2 Study of PX-866 and Docetaxel in
Patients with Solid Tumors
Lilly JVBA (IMCL CP12-1027): A Randomized, Double-Blind,
Phase 3 Study of Docetaxel and Ramucirumab versus Docetaxel and Placebo
in the Treatment of Stage IV Non-Small Cell Lung Cancer Following Disease
Progression after One Prior Platinum-Based Therapy
RTOG 0813: Seamless Phase I/II Study of Stereotactic
Lung Radiotherapy (SBRT) for Early Stage, Centrally Located Non-Small
Cell Lung Cancer (NSCLC) in Medically Inoperable Patients
Lymphoma
An Open-Label, Randomized, Phase 2 Study
to Assess the Effectiveness of
RCHOP With or Without VELCADE in Previously Untreated Patients with Non-Germinal
Center B-Cell-like Diffuse Large B-Cell Lymphoma
Pancreatic
A Phase 2 Randomized, Double-Blinded,
Placebo-Controlled Study to Evaluate the Efficacy and Safety of GS-6624
Combined with Gemcitabine as First Line Treatment for Metastatic Pancreatic
Adenocarcinoma
Neoadjuvant CAPOXIRI Chemotherapy in the Treatment of Resectable, Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma
Prostate
A Phase 1b/2 Study Of Docetaxel And Prednisone,
With Or Without ISIS 183750 (an eIF4E Inhibitor), In Patients With Castrate-Resistant
Prostate Cancer
ECOG 2809: Androgen Receptor Modulation:
Phase II, Randomized Study of MK-2206 - Bicalutamide Combination in Patients
With Rising PSA at High-Risk of Progression After Primary Therapy
Analysis of circulating tumor cells
in prostate cancer. Predicting response to taxanes: A Pilot Study
Image-Guided Intensity-Modulated Radiotherapy (IG-IMRT)
for Prostate Cancer
Renal
Proleukin® Observational Registry to Evaluate
the Treatment Patterns and Clinical Response in Malignancy
A Randomized Phase II Trial of Sunitinib/Gemcitabine
or Sunitinib in Advanced Renal Cell Carcinoma with Sarcomatoid Features
ECOG4805 -A Randomized Phase II Study to Determine
the Effect of 2 Different Doses of AVE0005 (VEGF Trap) in Patients with
Metastatic Renal Cell Carcinoma
Phase I Trial of Stereotactic Body Radiotherapy
(SBRT) of the Primary Tumor in Renal Cell Carcinoma (RCC)
A randomized, double-blind, placebo-controlled
phase III study to evaluate the efficacy and safety of pazopanib as adjuvant
therapy for subjects with localized or locally advanced RCC following
nephrectomy
Skin
Multicenter, non-randomized, prospective study for
the treatment of non-melanoma skin cancer (squamous cell cancer and basal
cell cancer) using Xoft Axxent Electronic Brachytherapy Treatment System
as the primary treatment for NMSC
Other
A Phase III Randomized, Placebo-Controlled,
Clinical Trial to Study the Safety and Efficacy of V212 in Adult Patients
with Solid Tumor or Hematologic Malignancy
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