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Click Here for a detailed listing of studies, formatted as a .pdf

Breast Cancer

A Randomized Multicenter, Double-Blind, Placebo-Controlled Comparison of Chemotherapy plus Trastuzumab plus Placebo versus Chemotherapy plus Trastuzumab plus Pertuzumab as adjuvant Therapy in Patients with Operable HER2-positive Primary Breast Cancer

LUX: An open label, randomised phase III trial of BIBW 2992 and vinorelbine versus trastuzumab and vinorelbine in patients with metastatic HER2-overexpressing breast cancer failing one prior trastuzumab treatment

AMG 162: A Randomized, Double-Blind, Placebo-Controlled, Multi-Center Phase 3 Study of Denosumab as Adjuvant Treatment for Women with Early-Stage Breast Cancer at High Risk of Recurrence (D-CARE)

PT-304: Prediction of Response to Neoadjuvant Chemotherapy in Women with Operable Breast Cancer

Lumpectomy and Brachytherapy as Salvage Treatment for Local Recurrences Following Breast Conservative Therapy

Investigating Radiation Therapy: The Accelerated RT Trial

Mammary Ductoscopy and Intraductal Biopsy for Women at High Risk for Developing Breast Cancer, for Women Presenting with Spontaneous Nipple Discharge, and for Women Diagnosed with Breast Cancer Undergoing Surgery to the Contralateral Breast

GI/Colon

A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of GS-6624 Combined with FOLFIRI as Second Line Treatment for Metastatic KRAS Mutant Colorectal Adenocarcinoma that Has Progressed Following a First Line Oxaliplatin- and Fluoropyrimidine-Containing Regimen.

A Phase III Trial Evaluating the Addition of Trastuzumab to Trimodality Treatment of HER2-Overexpressing Esophageal Adenocarcinoma.

A Phase II Study For Patients With Advanced Rectal Cancer Using Pre-Operative High Dose Rate Brachytherapy + Folfox Chemotherapy

A Phase III Trial of 6 Versus 12 Treatments of Adjuvant FOLFOX Plus Celecoxib or Placebo for Patients with Resected Stage III Colon Cancer.

A Phase III Randomized, Double-Blind Trial of Chemoembolization with or without Sorafenib in Unresectable Hepatocellular Carcinoma (HCC) in Patients with and without Vascular Invasion.

RTOG 0436: A Phase III Trials Evaluating the Addition of Cetuximab to Paclitaxel, Cisplatin, and Radiation for Patients with Esophageal Cancer Who Are Treated Without Surgery

Gynecology

Phase II Trial of Combination Pemetrexed (Alimta) and Carboplatin (Paraplatin) in Platinum Sensitive Recurrent Ovarian, Primary Peritoneal, and Fallopian Tube Carcinoma

GOG-0263: RANDOMIZED PHASE III CLINICAL TRIAL OF ADJUVANT RADIATION VERSUS CHEMORADIATION IN INTERMEDIATE RISK, STAGE I/IIA CERVICAL CANCER TREATED WITH INITIAL RADICAL HYSTERECTOMY AND PELVIC LYMPHADENECTOMY.

Head and Neck
Phase 1/2 Study of PX-866 and Docetaxel in Patients with Solid Tumors

A Phase 2b, Multi-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Three Different Doses of SCV‑07 in Attenuating Oral Mucositis in Subjects With Head and Neck Cancer Receiving Concurrent Chemotherapy and Radiotherapy.

Prospective Evaluation of Unilateral/Ipsilateral Neck Irradiation Combined with Amifostine in Selected Patients with Squamous Cell Carcinoma of the Head and Neck Who are Managed by Radiation Therapy.

RTOG 0920: A Phase III Study of Postoperative Radiation Therapy (IMRT) +/- Cetuximab for Locally-Advanced Resected Head and Neck Cancer

A phase I trial of adjuvant chemotherapy using cetuximab (c) and docetaxel (t) for N2b-3 HNSCC patients with positive pathologic residual neck diseases after concurrent chemoradiation (CRT)

A Phase III Randomized Trial of Chemotherapy With or Without Bevacizumab in Patients with Recurrent or Metastatic Head and Neck Cancer

Hematology

TTP: Phase II study of danazol with plasma exchange and steroids for the treatment of thrombotic thrombocytopenic purpura

Lung
Surgical Cytoreduction Followed by Intraoperative Intrathoracic Hyperthermic Chemotherapy Perfusion for the Management of Disseminated Pleural Malignancies

Phase 1/2 Study of PX-866 and Docetaxel in Patients with Solid Tumors

Lilly JVBA (IMCL CP12-1027): A Randomized, Double-Blind, Phase 3 Study of Docetaxel and Ramucirumab versus Docetaxel and Placebo in the Treatment of Stage IV Non-Small Cell Lung Cancer Following Disease Progression after One Prior Platinum-Based Therapy

RTOG 0813: Seamless Phase I/II Study of Stereotactic Lung Radiotherapy (SBRT) for Early Stage, Centrally Located Non-Small Cell Lung Cancer (NSCLC) in Medically Inoperable Patients

Lymphoma
Calistoga: A Phase 2 Study to Assess the Efficacy and Safety of CAL-101 in Patients with Indolent B-Cell Non-Hodgkin Lymphoma Refractory to Rituximab and Alkylating Agents.

SWOG 0816: A Phase II Trial of Response Adapted Therapy of Stage III-lV Hodgkin Lymphoma Using Early Interim FDG-PET Imaging

An Open-Label, Randomized, Phase 2 Study to Assess the Effectiveness of
RCHOP With or Without VELCADE in Previously Untreated Patients with Non-Germinal Center B-Cell-like Diffuse Large B-Cell Lymphoma

Pancreatic
A Phase 2 Randomized, Double-Blinded, Placebo-Controlled Study to Evaluate the Efficacy and Safety of GS-6624 Combined with Gemcitabine as First Line Treatment for Metastatic Pancreatic Adenocarcinoma

Neoadjuvant CAPOXIRI Chemotherapy in the Treatment of Resectable, Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma

Prostate
A Phase 1b/2 Study Of Docetaxel And Prednisone, With Or Without ISIS 183750 (an eIF4E Inhibitor), In Patients With Castrate-Resistant Prostate Cancer

ECOG 2809: Androgen Receptor Modulation: Phase II, Randomized Study of MK-2206 - Bicalutamide Combination in Patients With Rising PSA at High-Risk of Progression After Primary Therapy

Analysis of circulating tumor cells in prostate cancer. Predicting response to taxanes: A Pilot Study

Image-Guided Intensity-Modulated Radiotherapy (IG-IMRT) for Prostate Cancer

Renal
Proleukin® Observational Registry to Evaluate the Treatment Patterns and Clinical Response in Malignancy

A Randomized Phase II Trial of Sunitinib/Gemcitabine or Sunitinib in Advanced Renal Cell Carcinoma with Sarcomatoid Features

A Randomized Phase II Study to Determine the Effect of 2 Different Doses of AVE0005 (VEGF Trap) in Patients with Metastatic Renal Cell Carcinoma

Phase I Trial of Stereotactic Body Radiotherapy (SBRT) of the Primary Tumor in Renal Cell Carcinoma (RCC)

A randomized, double-blind, placebo-controlled phase III study to evaluate the efficacy and safety of pazopanib as adjuvant therapy for subjects with localized or locally advanced RCC following nephrectomy

Skin
Multicenter, non-randomized, prospective study for the treatment of non-melanoma skin cancer (squamous cell cancer and basal cell cancer) using Xoft Axxent Electronic Brachytherapy Treatment System as the primary treatment for NMSC