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A
Multi-Center, Open-Label, Randomized Clinical Trial Comparing the Efficacy
of Four Anti-Inflammatory Regimens in the Treatment Central Centrifugal
Cicatricial Alopecia
| Principal
Investigator: |
|
Andrew Alexis, MD |
| Co-investigators: |
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Marcelyn Coley, MD
Sejal Shah, MD
John Seykora, MD
|
| Time
frame of study: |
|
Ongoing |
| Time
frame of participation: |
|
Approximately 12 months |
| Number
of participants needed: |
|
20 |
| Location
of Study: |
|
St. Luke’s-Roosevelt Hospital
Center
1090 Amsterdam Avenue
Suite 11D
New York, NY 10025
|
| Contact
Name, Number & Email: |
|
Clinical Research Offiice
(212) 523-4511
MColey@chpnet.org |
Summary:
This is a multi-center, open-label, randomized, prospective
study to compare the efficacy of four anti-inflammatory treatment regimens
for the hair loss disorder, central centrifugal cicatricial alopecia (CCCA).
The 48-week study will be divided into 2 phases: a 24 week Anti-Inflammatory
phase (Phase 1) followed by a 24 week Stimulation of Growth phase (Phase
2). 20 female subjects will be recruited at each of 3 sites. Subjects
will be followed for a minimum of 48 weeks with interval visit assessments
after treatment is initiated for a minimum of 10 visits.
Criteria for
Participation:
-Female patients of African descent
-Ages 18-65
-Progressive hair loss that began on top, central part of the scalp
Benefits/Compensation:
Evaluation and treatment by a board
certified dermatologist
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